| 名稱 | AI-Edigene® FLT3 p.D835V Reference Standard P |
| 型號(hào) | CBP10509 |
| 報(bào)價(jià) |  |
| 特點(diǎn) | AI-Edigene® FLT3 p.D835V Reference Standard Plus |
產(chǎn)品搜索
相關(guān)文章
- 【產(chǎn)品推介】CD47&SIRPɑ 細(xì)胞篩選模型
- 黑色素瘤研究進(jìn)展一覽
- 【現(xiàn)貨上線】HRR-Related-28 Gene標(biāo)準(zhǔn)品
- 抗衰老全新靶點(diǎn)，抑制IL-11通路可延長(zhǎng)哺乳動(dòng)物壽命
- Cell Metab：雙信號(hào)通路失調(diào)協(xié)同促進(jìn)肺癌形成
- OX40&PD-1/L1雙免疫檢查點(diǎn)細(xì)胞篩選模型
- 細(xì)胞株鑒定指南
- 腫瘤細(xì)胞培養(yǎng)實(shí)驗(yàn)的主要用途
- 老靶點(diǎn)迭代突破創(chuàng)新：Her2靶點(diǎn)細(xì)胞模型
- 【產(chǎn)品推介】IL23抗體篩選模型
聯(lián)系我們
聯(lián)系人：蔣經(jīng)理
電話：4008750250
號(hào)碼：
手機(jī)：18066071954
地址：南京市棲霞區(qū)緯地路9號(hào)
Email： zhangxiangwen@cobioer.com
電話：4008750250
號(hào)碼：
手機(jī)：18066071954
地址：南京市棲霞區(qū)緯地路9號(hào)
Email： zhangxiangwen@cobioer.com
產(chǎn)品展示 / PRODUCTS
基因檢測(cè)標(biāo)準(zhǔn)品 > Mutation > CBP10509AI-Edigene® FLT3 p.D835V Reference Standard P
- 詳細(xì)內(nèi)容
CBP10509 | |
| Format | Genomic DNA |
| Description | FLT3 D835V lies within the protein kinase domain activation loop of the Flt3 protein (PMID: 11290608). D835V results in constitutive phosphorylation of Flt3 and activation of Stat5, Erk signaling, leading to transformation of cultured cells (PMID: 15256420), and has been demonstrated to promote secondary drug resistance in the context of FLT3 internal tandem duplication (FLT3-ITD) mutations (PMID: 22504184, PMID: 29187377). |
| Technical Data | |
| DNA Change | c.2504A>T |
| AA Change | p.D835V |
| Mutation type | Substitution - Missense |
| Zygosity | Homozygous |
| Allelic Frequency | 100% |
| Transcript | NM_004119.3 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |
|
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
會(huì)員_a.png)