產(chǎn)品搜索
相關(guān)文章
- PD-1/L1 &4-1BB雙靶點(diǎn)細(xì)胞篩選模型
- STR標(biāo)準(zhǔn)品上新
- 【轉(zhuǎn)載】抗癌路漫漫,又翻一座山,名曰“CD24”
- 實(shí)驗(yàn)?zāi)芊裰貜?fù)仍在持續(xù):誰(shuí)來(lái)給韓春雨事件畫上句號(hào)?
- 4-1BB(CD137)靶點(diǎn)藥物篩選模型
- BRCA1/BRCA2基因檢測(cè)標(biāo)準(zhǔn)品
- 選擇本公司的人結(jié)腸癌細(xì)胞株有3個(gè)理由
- ATCC細(xì)胞的培養(yǎng)方法
- STING激動(dòng)劑和拮抗劑的篩選
- 熒光素酶檢測(cè)試劑盒介紹
聯(lián)系我們
電話:4008750250
號(hào)碼:
手機(jī):18066071954
地址:南京市棲霞區(qū)緯地路9號(hào)
Email: zhangxiangwen@cobioer.com
產(chǎn)品展示 / PRODUCTS
藥靶細(xì)胞株 > kinase激酶細(xì)胞株 > CBP73253CSF3R T618I/BaF3

- 詳細(xì)內(nèi)容
CBP73253 | |
I. Introduction | |
Cell Line Name: | CSF3R T618I/BaF3 |
Host Cell: | Ba/F3 |
Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Application: | Anti-proliferation assay and PD assay |
Freeze Medium: | 90% FBS+10% DMSO |
Complete Culture Medium: | RPMI-1640+10%FBS |
Mycoplasma Status: | Negative |
II.Background | |
CSF3R T618I lies within the extracellular domain proximal to the transmembrane domain of the Csf3r protein (PMID: 23656643). T618I confers a gain of function to the Csf3r protein as demonstrated by increased proliferation and increased downstream Jak-Stat signaling in transformed cells in culture (PMID: 23656643). | |
III. Representative Data | |
1.WB of CSF3R T618I/BaF3 | |
2. Anti-proliferation assay | |
Figure 2. Anti-proliferation assay of three reference compounds on the CSF3R T618I/BaF3. |